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  1. Hox gene

    Hox genes, a subset of homeobox genes, are a group of related genes that specify regions of the body plan of an embryo along the head-tail axis of animals. Hox proteins encode and specify the characteristics of 'position', ensuring that the correct structures form in the correct places of the body. For example, Hox genes in insects specify which appendages form on a segment, and Hox genes in vertebrates specify the types and shape of vertebrae that will form. In segmented animals, Hox proteins thus confer segmental or positional identity, but do not form the actual segments themselves. Studies on Hox genes in ciliated larvae have shown they are only expressed in future adult tissues. In larvae with gradual metamorphosis the Hox genes are activated in tissues of the larval body, generally in the trunk region, that will be maintained through metamorphosis. Wikipedia

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  2. onlyzoology.com

    A. Hox gene mutations and their effects on body plan in model organisms B. Insights from fossil records and their implications for Hox gene evolution V. Conclusion A. Summary of the impact of Hox genes on body plan evolution B. Future directions for research in Hox gene studies and evolutionary biology REFERENCES
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  4. sciencedirect.com

    Hox genes are transcription factors that regulate the body plan and segment identity of tissues along the anterior-posterior axis. Learn about their roles in development, evolution, and human disorders from various chapters and articles on ScienceDirect.
  5. ncbi.nlm.nih.gov

    National Center for Biotechnology Information

    https://www.ncbi.nlm.nih.gov › books › NBK9978

    Slack and his colleagues (1993) postulated that the Hox gene expression pattern defines the development of all animals, and that the pattern of Hox gene expression is constant for all phyla.**The reason for this remarkable conservation of structure in the Hox gene complex is thought to be the sharing of cis-regulatory regions by neighboring genes.
  6. pubmed.ncbi.nlm.nih.gov

    Jan 1, 2023Abstract Hox genes encode evolutionarily conserved transcription factors that are essential for the proper development of bilaterian organisms. Hox genes are unique because they are spatially and temporally regulated during development in a manner that is dictated by their tightly linked genomic organization. Although their genetic function during embryonic development has been interrogated ...

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